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Version: 1.0.0 | Published: 26 Sep 2025 | Updated: 0 days ago

Beta-blocker Stratification using MRI to assess portal pressure (B-SMaRT)

Dataset

Documentation

Description:
Beta-blocker Stratification using quantitative MRI techniques to assess portal pressure and Response to Treatment in patients with portal hypertension (B-SMaRT study). To provide proof of concept that quantitative haemodynamic MRI markers can stratify the efficacy of carvedilol to lower clinically significant portal hypertension in patients with cirrhosis. Descriptive sequential pilot study of patients with cirrhosis, portal pressure measurement, research MRI (at 3T) and endoscopy with outcomes with repeat measures in those who are given Carvedilol.

Coverage

Typical Age Range:
18-80
Follow Up:
1 - 10 YEARS
Physical Sample Availability:
AVAILABILITY TO BE CONFIRMED
Pathway:
Secondary Care

Provenance

Origin

Purposes:
STUDY
Sources:
PAPER BASED
Collection Situations:
OUTPATIENTS

Temporal

Accrual Periodicity:
IRREGULAR
Start Date:
01 August 2016
Time Lag:
VARIABLE

Accessibility

Access

Access Rights:
In Progress
Delivery Lead Time:
VARIABLE
Jurisdictions:
GB-ENG
Data Controller:
Professor Guruprasad Aithal

Usage

Data Use Limitations:
GENERAL RESEARCH USE
Resource Creators:
  • NIHR Nottingham Biomedical Research Centre
  • Nottingham University Hospitals NHS Trust

Format and Standards

Vocabulary Encoding Schemes:
LOCAL
Languages:
en
Formats:
Database

Observations

Statistical Population
Population Description
Population Size
Measured Property
Observation Date
Persons
46
Count
01 August 2016